Nystatin: A Comprehensive Guide to Uses, Forms, Side Effects, and Savings with GoodRx

Nystatin is a well-established antifungal medication used to treat various fungal infections, particularly those caused by Candida species. Available in multiple formulations, it offers flexibility in addressing different types of infections. This guide provides an in-depth look at Nystatin’s uses, forms, potential side effects, and how to save on prescriptions using GoodRx.GoodRx+5GoodRx+5GoodRx+5

What Is Nystatin?

Nystatin belongs to the polyene class of antifungal agents. It works by binding to ergosterol, a key component of fungal cell membranes, creating pores that lead to cell death. Notably, Nystatin is not absorbed into the bloodstream when applied topically or taken orally, making it effective for localized infections without systemic effects.

Common Uses of Nystatin

Nystatin is primarily used to treat infections caused by Candida species. Its applications include:

Oral Thrush: Nystatin oral suspension is commonly prescribed for treating thrush, a yeast infection in the mouth and throat. Patients typically swish and swallow the suspension multiple times daily. GoodRx
Cutaneous Candidiasis: Topical forms of Nystatin, such as creams, ointments, and powders, are used to treat skin infections like diaper rash or intertrigo. GoodRx+2GoodRx+2GoodRx+2
Gastrointestinal Candidiasis: Nystatin tablets are taken orally to address yeast infections in the gastrointestinal tract. GoodRx

Available Formulations

Nystatin is available in several formulations to cater to different treatment needs:

Oral Suspension: Typically used for oral thrush, the suspension is swished in the mouth and swallowed.GoodRx+1GoodRx+1
Tablets: Used for treating gastrointestinal candidiasis, these are taken orally.
Topical Creams and Ointments: Applied directly to the skin to treat cutaneous infections.
Topical Powders: Useful for moist areas prone to fungal growth, such as skin folds.

It’s important to note that Nystatin is available only by prescription and is not sold over the counter.

Side Effects and Considerations

While Nystatin is generally well-tolerated, some individuals may experience side effects:

Oral Forms: Possible side effects include mouth irritation, nausea, vomiting, stomach upset, and diarrhea. GoodRx
Topical Forms: Some users may experience itching or burning at the application site. GoodRx+3GoodRx+3GoodRx+3

If side effects are severe or persistent, it’s advisable to consult a healthcare provider.

Cost and Savings with GoodRx

Nystatin is available as a generic medication, which helps keep costs relatively low. However, prices can vary based on the pharmacy and formulation. GoodRx offers coupons and discounts that can significantly reduce out-of-pocket expenses:GoodRx+2GoodRx+2GoodRx+2 GoodRx

Oral Suspension (60 mL): Prices can be as low as $6.46 with a GoodRx coupon. GoodRx+4GoodRx+4GoodRx+4
Tablets (120 tablets of 500,000 units): Approximately $45.48 with a GoodRx coupon, representing a 66% discount from the average retail price. GoodRx
Topical Creams/Ointments (30g tube): Around $13.73 with a GoodRx coupon, offering a 45% savings. GoodRx

Patients are encouraged to compare prices at different pharmacies and use GoodRx coupons to obtain the best possible price.

Comparisons with Other Antifungals

Nystatin is often compared to other antifungal medications:GoodRx+6GoodRx+6GoodRx+6

Clotrimazole: Available over the counter, clotrimazole treats a broader range of fungal infections, including athlete’s foot and jock itch. However, Nystatin is specifically effective against Candida infections. GoodRx+2GoodRx+2GoodRx+2
Fluconazole (Diflucan): An oral antifungal that treats systemic infections. While effective, fluconazole may have more systemic side effects compared to Nystatin. GoodRx

The choice between these medications depends on the type and severity of the infection, as well as patient-specific factors.GoodRx+3GoodRx+3GoodRx+3

Conclusion

Nystatin remains a cornerstone in the treatment of Candida-related infections, offering various formulations to address different clinical needs. Its generally favorable safety profile and cost-effectiveness, especially when combined with GoodRx discounts, make it a valuable option for patients and healthcare providers alike. As with any medication, it’s essential to use Nystatin under the guidance of a healthcare professional to ensure optimal outcomes.

May 26, 2025