Norepinephrine Infusion Calculator
Precisely Calculate mcg/kg/min to mL/hr Conversion
For medical professionals in ICU, ER, and critical care settings
Calculator
Infusion Rate Result
The required infusion rate is:
for a patient of 0 kg at 0 mcg/kg/min
Formula Used:
Infusion Rate (mL/hr) = [Dose (mcg/kg/min) × Weight (kg) × 60] / Concentration (mcg/mL)
About Norepinephrine
- Indications: Treatment of acute hypotension, septic shock, and cardiogenic shock
- Mechanism: Potent alpha-adrenergic agonist with some beta-adrenergic activity
- Onset: Rapid onset (1-2 minutes) when administered IV
- Half-life: Approximately 2-3 minutes
- Typical Dosing: 0.01-3 mcg/kg/min titrated to effect
Important Considerations
Norepinephrine is a high-alert medication. Always use an infusion pump and confirm dosing with another clinician when possible. Monitor blood pressure, heart rate, and peripheral perfusion continuously.
Clinical Tips
• Always use central venous access for administration
• Titrate slowly to achieve target MAP (usually ≥65 mmHg)
• Monitor for extravasation – can cause tissue necrosis
• Wean gradually once hemodynamic stability is achieved
Norepinephrine Infusion Calculator – Critical Care Dosing
This norepinephrine calculator simplifies the complex process of converting mcg/kg/min doses to practical mL/hr infusion rates for healthcare providers. Accurate calculation of vasopressor infusions is essential in critical care settings such as intensive care units (ICU), emergency departments (ER), and operating rooms.
Norepinephrine (Levophed) is a potent alpha-adrenergic receptor agonist used as a first-line vasopressor in septic shock and other forms of vasodilatory shock. Proper dosing is crucial as both under-dosing and over-dosing can have significant clinical consequences.
Key Features of This Calculator:
- Accurate conversion from mcg/kg/min to mL/hr infusion rates
- Pre-configured common concentrations (4mg/250mL, 8mg/250mL, 16mg/250mL)
- Option for custom concentration inputs
- Instant results with clear formula explanation
- Mobile-responsive design for use at bedside
- Clinical considerations and safety information
This tool is designed for healthcare professionals including physicians, nurses, nurse practitioners, physician assistants, pharmacists, and critical care paramedics. Always verify calculations and follow institutional protocols for vasopressor administration.